SYNTHESIS AND STRUCTURE OF HYDRAZONE-DERIVATIVE DIALKYLKETIPINATS

Tarasova Viktoriya Alekseevna, Postgraduate student, Orenburg State University; expert of the department of pharmaceutical management department, Ministry of healthcare of Orenburg region (33 Tereshkovoy street, Orenburg, Russia), rianna@bk.ru
Mukovoz Petr Petrovich, Candidate of chemical sciences, leading researcher, Institute of cell and intracellular symbiosis of the Ural branch of the Russian Academy of Sciences (11 Pionerskaya street, Orenburg, Russia), mpp27@mail.ru
Koz'minykh Vladislav Olegovich, Doctor of chemical sciences, professor, head of sub-department of chemistry, Perm State Pedagogical University (24 Sibirskaya street, Perm, Russia), kvoncstu@yahoo.com

547.341+547.725

Background. 1,3,4,6-Tetracarbonyl systems are successfully used in organic synthesis and coordination chemistry as perspective semi-functional nanomaterials and bioactive substances. Chemistry of such representatives of tetracarbonyl compounds as ethers of 3,4-dihydroxy-2,4-hexadiene-1,6-ketipic acid until the present research remained unsufficiently studied. The aim of the article is to supplement the data of dialkylketipinat chemistry and to study the structural features of new nitrous derivatives of the basis thereof.
Materials and methods. The authors used alkylacetates, dialkyloxalates and sodium hydrides as parent compounds for obtainment of dialkylketipinats. The method of new hydrazine derivatives obtainment was a reaction of dialkylketipinats with 2,4-dinitrophenilhydrazine in the environment consisting of ethanol with glacial acetic acid.
Results. The authors developed a method of obtaining various ethers of 3-[2-(2,4-dinitrophenil)hydrazone]hexane-1,6-ketipic acid and ethers of 3,4-bis [2-(2,4-dinitrophenil)hydrazone]hexane-1,6-ketipic acid. The researchers studied the structural features of the synthesized compounds on the basis of data obtained by infrared and nuclear magnetic resonance spectroscopy.
Conclusions. The authors studied the reaction of dialkylketipinats with 2,4-dinitrophenilhydrazine, resulting in obtainment of new hydrazine derivatives. The researchers investigated the structural features of the synthesized compounds and established that the ketipinats may form both monohydrazone-derivative and bishydrazones depending on the conditions. It is shown that the hydrazine derivatives of ketipinats in solidcondition are associated, and insolutions there is no association.

1,3,4,6-tetracarbonyl compounds, dialkylketipinats, 2,4-dinitrophenilhydrazine, hydrazine derivatives of ketipinats.

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