Kormishina Alyona Evgen'evna, Senior lecturer, sub-department of general and clinical pharmacology with a course of microbiology, Ulyanovsk State University (42 L. Tolstogo street, Ulyanovsk, Russia), email@example.com
Mizina Praskov'ya Georgievna, Doctor of pharmacological sciences, professor, deputy director, All-Russian Research Institute of Medicinal and Aromatic Plants (building 1, 7 Grina street, Moscow, Russia), firstname.lastname@example.org
Melenteva Elena Stanislavovna, Deputy director general formedical treatment, “Ulyanovskkurort” Plc. (5 Dvortsovaya street, Ulyanovsk, Russia), email@example.com
Kozlov Dmitriy Vladimirovich, Candidate of physical and mathematical sciences, director of the center of collective use of scientific equipment, head of the materials science laboratory, Ulyanovsk State University (42 L. Tolstogo street, Ulyanovsk, Russia), firstname.lastname@example.org
Background. Various natural and synthetic materials may be sources of enterosorbents. Natural mineral clay arouses certain scientific and practical interest. And in this aspect, Undory therapeutic clay can be regarded as a promising enterosorbent.
Materials and methods. The authors studied Kimmeridgian (blue) “Undory” therapeutic powder clay (TU 9369-002-02590678-2006) in terms of a possibility of creating domestic sorption materials for medical practice on its basis. The elemental composition was studied by mass spectrometry with ionization via an inductively coupled argon plasma spectrometer ICAP-6500 Duo (Thermo Electron Corporation, USA). The fractional composition of the clay was determined by X-ray diffraction using an X-ray diffractometer Bruker Phaser D2 (Germany). The microstructure wasinvestigated by a scanning electron microscope Phenom ProX at 15 kV (detector SEM, electron beam size – 30) in high vacuum. The images were processed in a ProSuite software package of automated solutions. The specific surface area was determined by physical sorption of nitrogen via the BET method (Brunauer-EmmetTeller) on a Carlo ErbaSorpty 1750 device (Italy).
Results and conclusions. The data allow to consider Undory therapeutic clay as a promising source of domestic sorption materials for medical practice.
1. Nikolaev V. G. Vestnik problem biologii i meditsiny [Bulletin of biological and medical problems]. 2007, no. 4, pp. 7–17.
2. Belyakov N. A., Solomennikov A. V. Efferentnaya terapiya [Efferent therapy]. 1997, no. 2, pp. 115–128.
3. Nikolaev V. G., Mikhalovskiy S. V., Gurina N. M. Efferentnaya terapiya [Efferent therapy]. 2005, vol. 11, no. 4, pp. 3–17.
4. Travinka V. M. Golubaya tselitel'nitsa glina [Therapeutic blue clay]. Saint-Petersburg, 2007, pp. 28–74.
5. Rabochiy proekt razrabotki i rekul'tivatsii «Undorovskogo» mestorozhdeniya lechebnykh glin, raspolozhennogo v Ul'yanovskom rayone Ul'yanovskoy oblasti. T. 1. Tekhnologicheskaya chast' [A working draft of development and restoration of the “Undory” therapeutic clay deposit, located in Ulyanovsk district of Ulyanovsk region. Vol. 1. Technlological section]. Saratov, 2005, pp. 117–134.
6. GOST 17.4.1.02–83. Okhrana prirody. Klassifikatsiya khimicheskikh veshchestv dlya
kontrolya zagryazneniya [State standard 17.4.1.02–83. Environmental protection. Classification of chemical substances for pollution monitoring]. Moscow, 1983, 12 p.
7. Adilov V. B., Berezhnov E. S., Borovnitskiy I. P. Klassifikatsiya mineral'nykh vod i lechebnykh gryazey dlya tseley ikh sertifikatsii: metod. ukazaniya № 2000/34 [Classification of mineral waters and peloids for certification thereof: instructional guidelines № 2000/34]. Moscow, 2000.
8. Zhilyakova E. T., Bondarev A. V. Farmatsiya i farmakologiya [Pharmacy and pharmacology]. 2014, no.2, pp.3–5.
9. Grim R. E. Mineralogiya i prakticheskoe ispol'zovanie glin [Mineralogy and practical use of clay]. Transl. from English by V. I. Fin'ko, S. S. Chekina. Moscow: Mir, 1967, 512 p.